Human leukocyte antigen HLADRB1 determinants susceptibility to gastroesophageal reflux disease
نویسندگان
چکیده
منابع مشابه
Human leukocyte antigen HLADRB1 determinants susceptibility to gastroesophageal reflux disease.
BACKGROUND - Gastroesophageal reflux disease (GERD) is characterized by diverse symptoms. There is an evidence for a genetic component to GERD as supported by familial aggregation of this disease. OBJECTIVE - To investigate whether certain human leucocyte antigen genes HLA-DRB1 are associated with GERD. METHODS - Patients and controls were prospectively recruited from GIT center at Al-Kindy...
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Diagnosis History. If classic symptoms of heartburn and acid regurgitation dominate a patient’s history, then they can help establish the diagnosis of GERD with sufficiently high specificity, although sensitivity remains low compared to 24-hour pH monitoring. The presence of atypical symptoms (Table 1), although common, cannot sufficiently support the clinical diagnosis of GERD [B*]. Testing....
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CC This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. *Correspondence: Ching-Liang Lu, MD Division of Gastroenterology, Department of Medicine...
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Gastroesophageal reflux is the involuntary movement of gastric contents to the esophagus. It is a common disease, occurring in one third of the population in the United States. However, reflux is only considered a disease when it causes frequent or severe symptoms or when it produces injury. About 3–7% of the U.S. population suffers from frank esophageal reflux disease. Most reflux disease is n...
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ژورنال
عنوان ژورنال: Arquivos de Gastroenterologia
سال: 2017
ISSN: 0004-2803
DOI: 10.1590/s0004-2803.2017v54n1-08